METHYL 3,3,3-TRIFLUOROALANINATE
Methyl 3,3,3-trifluoroalaninate
CAS: 27240-44-4
Molecular Formula: C4H6F3NO2
METHYL 3,3,3-TRIFLUOROALANINATE - Names and Identifiers
METHYL 3,3,3-TRIFLUOROALANINATE - Physico-chemical Properties
| Molecular Formula | C4H6F3NO2 |
| Molar Mass | 157.09 |
| Density | 1.325±0.06 g/cm3(Predicted) |
| Melting Point | 168-170°C |
| Boling Point | 147.5±35.0 °C(Predicted) |
| pKa | 2.70±0.50(Predicted) |
METHYL 3,3,3-TRIFLUOROALANINATE - Risk and Safety
| Risk Codes | 36 - Irritating to the eyes |
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| Hazard Note | Toxic |
METHYL 3,3,3-TRIFLUOROALANINATE - Introduction
Methyl 3,3,3-trifluoroalaninate, chemical formula CF3CH2COOCH3, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: Methyl 3,3,3-trifluoroalaninate is a colorless liquid.
-Melting point: Its melting point is about -85°C.
-Boiling point: Its boiling point is about 78°C.
-Solubility: Soluble in some organic solvents, such as ethers, alcohols and chlorinated hydrocarbons.
Use:
-Chemical synthesis: Methyl 3,3,3-trifluoroalaninate can be used as a reagent in organic synthesis, for example, it can be used to synthesize other compounds, or as a raw material for catalysts.
-Drug research: It can also be used in drug research as an intermediate or reactant.
-Pesticide research and development: In the field of pesticide research and development, it can be used as a synthetic intermediate for certain pesticides.
Preparation Method:
the synthesis method of Methyl 3,3,3-trifluoroalaninate mainly has the following two commonly used processes:
1. by the reaction of trifluoropropanol and methyl chloroformate to generate 3,3,3-trifluoropropionyl chloride, and then react with ammonia to generate 3,3,3-trifluoropropionamide. Methyl 3,3,3-trifluoroalaninate can be obtained by esterification with methanol.
2. Another commonly used synthesis method is to react trifluoropropionaldehyde and methanol to generate methyl 3,3, 3-trifluoropropionate, and then react with methionine to generate Methyl 3,3,3-trifluoroalaninate.
Safety Information:
Since Methyl 3,3,3-trifluoroalaninate is an organic compound, it has a certain degree of danger. In the use of the process need to pay attention to the following matters:
-pay attention to ventilation: use to maintain good ventilation, avoid inhalation of its vapor.
-Personal protection: Personal protective equipment such as chemical protective gloves, goggles and protective clothing is required.
-Storage and handling: should be stored in a cool, dry place, away from fire and oxidizing agents.
Please note that before using or operating any organic compound, please be sure to understand the properties of the compound in detail, and follow the correct operating procedures and safety measures. In a laboratory environment, it is also important to follow the laboratory's safe operating guidelines.
Nature:
-Appearance: Methyl 3,3,3-trifluoroalaninate is a colorless liquid.
-Melting point: Its melting point is about -85°C.
-Boiling point: Its boiling point is about 78°C.
-Solubility: Soluble in some organic solvents, such as ethers, alcohols and chlorinated hydrocarbons.
Use:
-Chemical synthesis: Methyl 3,3,3-trifluoroalaninate can be used as a reagent in organic synthesis, for example, it can be used to synthesize other compounds, or as a raw material for catalysts.
-Drug research: It can also be used in drug research as an intermediate or reactant.
-Pesticide research and development: In the field of pesticide research and development, it can be used as a synthetic intermediate for certain pesticides.
Preparation Method:
the synthesis method of Methyl 3,3,3-trifluoroalaninate mainly has the following two commonly used processes:
1. by the reaction of trifluoropropanol and methyl chloroformate to generate 3,3,3-trifluoropropionyl chloride, and then react with ammonia to generate 3,3,3-trifluoropropionamide. Methyl 3,3,3-trifluoroalaninate can be obtained by esterification with methanol.
2. Another commonly used synthesis method is to react trifluoropropionaldehyde and methanol to generate methyl 3,3, 3-trifluoropropionate, and then react with methionine to generate Methyl 3,3,3-trifluoroalaninate.
Safety Information:
Since Methyl 3,3,3-trifluoroalaninate is an organic compound, it has a certain degree of danger. In the use of the process need to pay attention to the following matters:
-pay attention to ventilation: use to maintain good ventilation, avoid inhalation of its vapor.
-Personal protection: Personal protective equipment such as chemical protective gloves, goggles and protective clothing is required.
-Storage and handling: should be stored in a cool, dry place, away from fire and oxidizing agents.
Please note that before using or operating any organic compound, please be sure to understand the properties of the compound in detail, and follow the correct operating procedures and safety measures. In a laboratory environment, it is also important to follow the laboratory's safe operating guidelines.
Last Update：2024-04-09 21:04:16
